Life Sciences

Nanoscience and High Performance Computing

Nanotube

High Performance Computing is used in nanoscience to investigate the relationship between the size, shape and structure of nanoscale materials (nanomorphology) and the thermal and chemical environment

Modelling HIV Reverse Transcriptase

HIV reverse transcriptase

High performance computing was used to investigate the effects of resistance mutations within a crucial enzyme of Human Immunodeficiency Virus (HIV) towards the antiviral drug Nevirapine.

Modelling HIV Protease Mutations

Aprenavir binding site showing water interactions

High performance computing was used to investigate the effects of resistance mutations within a crucial enzyme of Human Immunodeficiency Virus (HIV) towards a range of antiviral drugs.

Cadherin Modelling

Cadherin WT and Mutant Models

Cadherins are a class of calcium dependent molecules which are responsible for adhesion between cells.